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How do I get Xiaflex through my insurance?

Xiaflex · collagenase clostridium histolyticum · Provider-administered collagenase injection

Xiaflex / collagenase clostridium histolyticum

Office-administered specialty injection with two very different coverage pathways: Dupuytren’s contracture and Peyronie’s disease. Diagnosis-specific criteria and trained-provider requirements matter.

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1
WHY IS THIS MEDICINE BEING GIVEN?

Choose the diagnosis / reason.

Coverage rules can change by diagnosis and sometimes by formulation.

FINANCIAL HELP

Find help with your out-of-pocket costs.

Use the official support program below to check savings, patient-assistance, or access options that may apply to you.

XIAFLEX cost & copay support →
IF COVERAGE GETS STUCK

The medicine may be only part of the problem.

Use the playbook that matches what is blocking treatment, then verify the current rule with the insurer, program or treatment site.

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Important

MedicineCostHelp is an educational navigation tool, not an insurer and not a coverage determination. Medical policies, billing codes, product preferences and benefit placement can change. Sources were reviewed 2026-08-20. Verify the current official source before acting.

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