Plans may steer certain infusions toward lower-cost sites, but the patient’s clinical needs, network, drug sourcing and treatment-site capabilities still matter. ASHP notes that payer site-of-care restrictions can disrupt continuity and create missed infusions.

If the requested site is denied, identify whether the problem is network status, a site-of-care policy, specialty-pharmacy sourcing, or a medical-necessity determination. Each has a different fix.

Questions to answer before the next call or submission
  • Written site-of-care denial/restriction
  • Current site network status
  • Allowed site types
  • Exception criteria
  • Patient-specific medical reason if applicable
  • Alternative site capability
  • Authorized product sourcing
  • Administration authorization
  • Continuity/timing plan

Get the site-specific reason in writing

Ask what site types are permitted: physician office, freestanding infusion center, hospital outpatient department, home infusion or other setting. Confirm whether the current site is denied because of network, cost, policy or clinical criteria.

Request the policy and exception process rather than accepting “must go somewhere cheaper” as the complete explanation.

Have the prescriber explain why this site matters if clinically necessary

Examples can include monitoring needs, prior reaction history, emergency support, complex comorbidities, dose preparation, coordination with another service or a product that the proposed site cannot safely provide. The reason must be patient-specific.

Operational convenience alone may not meet the plan’s exception standard, so distinguish medical need from preference.

Confirm the alternative site can actually deliver the authorized treatment

Before transferring care, verify the site is in network, can obtain the exact authorized product, accepts the required drug-sourcing model and can meet the treatment schedule.

If the alternative cannot provide the treatment, document that barrier and return it to the plan as part of the exception request.

Use the source that actually controls your case

MedicineCostHelp can organize the problem, but the member-specific plan, payer decision, provider record or assistance program makes the actual determination. Keep written decisions, reference numbers and the documents that support the next step.